Hirudin is the most potent natural inhibitor of both soluble and clot-bound thrombin and binds thrombin at 1:1 stoichoimetry with high affinity. Hirudin is a ~7 kDa acidic protein and contains 65 amino acid residues. Hirudin can be used in any in vitro laboratory research application where an efficient inhibition of thrombin is required. Key data:
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